From Parallel Mesh Generation to Real-Time Image-to-Mesh Conversion for Image Guided Therapy Nikos Chrisochoides Computer Science Department The College of William and Mary Abstract: The first medical image, an X-ray taken by Rotgen in 1895, depicted his wife's wedding ring and her hand's bones. Today operating room suites are capable to produce hybrid data sets with both anatomic and metabolic information for more accurate tumor delineation. In this talk, I will present few results from my basic and translational research activities on parallel mesh generation and Image-to-Mesh (I2M) conversion for Image Guided Neurosurgery. First, I will overview some of my contributions on parallel guaranteed quality mesh generation which is critical technology for real-time I2M conversion. Then I will present some of my current research activities on I2M for medical image computing. I will conclude with my future plans in high-end computing and real-time medical image computing. Biography: Nikos Chrisochoides is a Professor of Computer Science, John Simon Guggenheim Fellow in Medicine and Health and founder and director of the Center for Real-Time Computing. His research interests are in medical image computing and high-end computing. He works both on theoretical and implementation aspects of parallel scientific computing. His research is application-driven. Currently he is working on real-time image-to-mesh conversion for biomedical applications like non-rigid registration and medical simulators for Image Guided Neurosurgery. Nikos received his Ph.D. in 1992 from Computer Science at Purdue University. He worked at Northeast Parallel Architectures Center in Syracuse, Advanced Computing Research Institute at Cornell Theory Center and the Department of Computer Science and Engineering at the University of Notre Dame. He received an SUR IBM Award in 1998, NSF Career Award in 1999, since then he received about $4.6M research funds and participated in basic research projects of about $10M. In 2000 he moved to the College of William and Mary as an Associate Professor and in 2004 he was awarded the Alumni Memorial Distinguished Professorship for "excellence in research and demonstrated commitment to teaching". He has held visiting positions at MIT and Harvard Medical School (Spring 2005), Brown University (Fall 2004) and NASA/Langley (Summer 1994).